Journal of Yeungnam Medical Science

Doo Jin Lee

13 Articles

A Case of Leiomyoma of The Lateral Vaginal Wall.: Sung Chul Park, Doo Jin Lee, Sung Ho Lee, Yoon Ki Park; Yeungnam Univ J Med. 2008;25(2):124-127. Published online December 31, 2008; DOI: https://doi.org/10.12701/yujm.2008.25.2.124

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Abstract PDF: Leiomyomas are common in the myometrial layer of the uterus, though they are rarely found in other reproductive organs. Leiomyomas are benign, hormone-sensitive smooth muscle tumors. They develop during the reproductive years and regress after menopause. Preoperative diagnosis is difficult to make. We present a case of a 54-year-old woman with a vaginal wall tumor. The management in this case included surgical excision. Histologic examination definitively confirmed the diagnosis of a vaginal leiomyoma. We report the details of this case along with a brief review of the literature.

Clinical Significance of Interleukin-6 Concentration of Cervical Discharge in Pregnant Women with Preterm Labor and Preterm Rupture of Membrane: Seong Woong Kim, Sung Chul Park, Sung Ho Lee, Doo Jin Lee; Yeungnam Univ J Med. 2007;24(2 Suppl):S505-518. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S505

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Abstract PDF: Background
：This study is conducted to determine the clinical efficacy of measurement of IL-6 concentration in cervical discharge as a biochemical predictor of preterm labor and PROM. Materials and Methods：Twenty-two pregnant women with preterm labor and 28 women with preterm rupture of membrane(PROM) between 20-36 gestational weeks were selected as study group, and 26 normal pregnant women were selected as control group. In both groups, following routine antenatal laboratory tests, concentration of interleukin-6(IL-6) in cervical discharge and amniotic fluid(in case of preterm labor and PROM) were estimated, and maternal C-reactive protein(CRP) level and WBC count were checked also. To compare the microbiological environment of both groups, Gram stain and culture of cervical smear were undertaken.
Results
：There were no significant differences in maternal age, gravity, parity, gestational age at sampling, and prior preterm delivery, but there were significant differences in initial cervical dilation, effacement, cervicovaginal pH, and preterm delivery in each groups. The average IL-6 level of cervical discharge in women with preterm labor and PROM were significantly higher than control group (p＜0.01). The distribution of women with preterm labor and PROM were significantly different from control group, when 186.7 pg/mL was selected as cutoff value(p＜0.01). There was strong positive correlation between IL-6 concentration in cervical discharge and amniotic fluid IL-6 concentration (r=0.865, p＜0.05). There was no significant difference in CRP in each groups. Maternal WBC count of PROM group at admission was higher than that of preterm labor and control group, but was not statistically significant (p=0.062). Gram (-) rods was detected frequently in women with preterm labor and PROM than control group (p＜0.05). The distribution of microorganisms in cervical discharge in women with preterm labor and PROM were different from control group. Conlusion：The results of this study suggested that cervical IL-6 concentration could be used as an indicator detecting the high risk pregnant women who might develop preterm labor and PROM, and could be accepted as a noninvasive diagnostic marker of intrauterine infection.

A Case of Clear Cell Adenocarcinoma of the Uterine Cervix: Sung-Chul Park, Yoon-Ki Park, Doo Jin Lee, Sung-Ho Lee; Yeungnam Univ J Med. 2007;24(2 Suppl):S652-657. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S652

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Abstract PDF: Clear cell adenocarcinoma of cervix is a very rare malignancy of the uterine cervix. The etiology and pathogenesis are unclear. Clear cell adenocarcinomas have been reported most commonly in women with a history of in utero exposure to diethylstilbesterol (DES), these tumors also can develope in the absence of exposure to DES. These tumors account for 4% to 9% of adenocarcinomas of the cervix. We report a case of clear cell adenocarcinoma in the uterine cervix of 40 years-old women who was not related to DES with a brief review of literature.

Two Cases of Congenital Vaginal Absence: Sung Chul Park, Hyun Jin Shin, Hyo Hyun Kim, Tae Hyung Lee, Sung Ho Lee, Doo Jin Lee; Yeungnam Univ J Med. 2007;24(2 Suppl):S710-718. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S710

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Abstract PDF: Congenital absence of vagina(Mayer-Rokitansky-Küster-Hauser syndrome) is found between 1 in 4,000 and 20,000 female births, and is frequently associated with various urinary tract and skeletal anomalies. As the patients have normal ovarian functions, they appear as normal female phenotype and have normal female karyotype 46, XX. Inability of coitus is one of the main problems they have, so the goal of treatment is to create a vagina adequate to allow sexual activity. Both surgical and nonsurgical approaches have been utilized. The authors experienced two cases of congenital absence of vagina successfully treated by surgical and nonsurgical method.

A Case of Uterine Didelphys with Obstructed Hemivagina and Ipsilateral Renal Agenesis: Sung Chul Park, Doo Jin Lee, Sung Ho Lee, Yoon Ki Park; Yeungnam Univ J Med. 2007;24(2 Suppl):S737-741. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S737

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Abstract PDF

Frequency of female genital congenital abnormality is about 0.2%. We suspect female as uterine abnormality with hematocolpos, who after menarche with progressive abdominal pain during menses, in associated with the finding of growing pelvic mass and not visible unilateral kidney at urography. Commonly it was fined with acute lower abdominal pain at puberty. Early diagnosis is very important to treatment and to fertility of patient. The simple and adequate treatment of the condition is incision of the obstructed vaginal septum providing adequate drainage of the retained blood. If diagnosis of this disease is late, it may occur complications of hematocolpos, hematosalphinx, endometriosis and pelvic adhesions by flowing backward of mensturational blood. Also it may cause decreasing fertility and secondary infection. We report a case of uterine didelphys with obstructed hemivagina and ipsilateral renal agenesis with a brief review of the literature.

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A Case Report on Secondary Dysmenorrhea with Herlyn-Werner-Wunderlich Syndrome
Pyung-Wha Kim, Ji-Yeong Im, Yong-Tae Jeon, Eun-Hee Lee
The Journal of Oriental Obstetrics and Gynecology.2016; 29(4): 69. CrossRef

Cervicography as a Screening Test for Cervical Cancer.: Doo Jin Lee, Sung Ho Lee; Yeungnam Univ J Med. 1999;16(2):169-180. Published online December 31, 1999; DOI: https://doi.org/10.12701/yujm.1999.16.2.169

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Abstract PDF

BACKGROUND
Uterine cervical cancer is the most common malignant tumor of the women in Korea. This study was undertaken to evaluate the usefulness of the cervicography as a screeningg test of cervical cancer. MATERIALS AND METHODS: Cervicography was taken from 482 women at department of obstetrics and gymecology, at Yeungnam University Hospital from March 1, 1998 to October 31, 1999, of the 482 women, 172women were excluded from the study for various reasons, and 310 women completed the study. Three-hundred and ten women had cervical cytology(Papanicolaou smear), cervicography and colposcopy, and punch biopsy was undertaken if any of the test result was abnormal. RESULTS: The most common age group was 35-39, and 40-44, 45-49 in order and most common reason for having a screening test was regular check for cervical cancer. The mean duration from the last Pap smear was 17.1 months, and 64 women(20.4%) never had any prior screening tests. Of the 310 women, 254 women were categorized as normal or having benign disease such as cervicitis, erosion or metaplasia. Biopsy was taken from 56 patients and the results were 26 chromic cervicitis, 4 mild dysplasia, 6 moderate dysplasia, 2 severe dysplasia, 14 carcinoma in situ and 4 invasive carcinoma. The results of cytology and cervicography were well correlated(p<0.05) The sensitivity of cytology and cervicography were 86.7% and 76.9%, respectively and the sensitivity and specificity of cervicography were 56.7% and 96.2%, respectively. False negative rate of cervicography(43.3%) was much higher than those of cytology(13.3%)(p<0.05), but false positive rate of cervicography(3.8%) was much lower than that of cytology(23.1%)(p<0.05). CONCLUSION: It seems inappropriate to use cervicography as a single scerrning test for cervival cancer, but it may be an effective complementary test for cytology to lower the false negative rate of cytology.

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Physico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates
Kanchan Lata Singh, Afshan Siddiqui, Kajal Singh, U.N. Tripathi
Chemistry & Chemical Technology.2019; 13(4): 407. CrossRef

A Clinical Study of 20 Uterine Sarcomas.: Young Gi Lee, Yoon Kee Park, Doo Jin Lee; Yeungnam Univ J Med. 1998;15(2):275-285. Published online December 31, 1998; DOI: https://doi.org/10.12701/yujm.1998.15.2.275

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Abstract PDF: Sarcoma of the uterus is very rare malignant tumor originating from uterine muscle or connective tissue. We have experienced 20 cases of uterine sarcoma from January 1991 to June 1998. The results were as follows: 1. The pathologic types were 13 cases(65.0%) of leiomyosarcoma, 5 cases(25.0%) of malignant mixed Mullerian tumor, 1 case of rhabdomyosarcoma, and 1 case of angiosarcoma. 2. The average age and parity was 50.2 and 3.7. The chief complaints were irregular vaginal bleeding(35.0%), lower abdominal pain(25.0%), and abdominal mass(25.0%). 3. Nine cases(45.0%) were FIGO stage I, 1 case(5.0%) was stage II, 6 cases(30.0%) were stage III, and 4 cases(20.0%) were stage IV. 4. The survival was from 1.5 months to over 130 months(median 16.5 months), and there was no correlation between survival and FIGO stage or pathologic type. The correlation between survival and number of mitotic figure was incalcurable. 5. CA 125 levels were serially measured as a tumor marker in monitoring patients and the positive rate was 40%. Further study was needed to make a conclusion for usefulness of CA 125 as a tumor marker.

Maternal Weight Gain Pattern and Birth Weight.: Mok Jin Kim, Ho Yeol Lee, Young Gi Lee, Yoon Ki Park, Doo Jin Lee, Sung Ho Lee; Yeungnam Univ J Med. 1998;15(1):135-142. Published online June 30, 1998; DOI: https://doi.org/10.12701/yujm.1998.15.1.135

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Maternal weight gain during pregnancy has been consistently associated with infant birth weight and pregnancy outcome. Our purpose was to determined the relationship between maternal weight gain pattern and birth weight. Consequently, maternal weight gain is monitored carefully and is encouraged during prenatal care in order to improve pregnancy outcome. Our study group included both 424 uncomplicated women and infant delivered at the Yeungnam University Hospital between 1993-1996. All recorded prenatal weight gain measurements were used to estimate maternal trimester weight gain, pattern of gain (based on low versus not-low gain at each trimester), and total gain at delivery. Multiple linear regression analysis was used to assess the relationship between these weight gain measurements and fetal birth weight. Each kilogram of maternal gain in the first, second, and third trimesters was associatedwith statistically related to the increase in fatal birth weight by 31.3, 19.0, and 24.5g, respectively. When compaired with the pattern of gain that was not low in any trimester, patterns with low gain in the first trimesters were associated with significant decreases in birth weight, but no important change in birth weight was seen for the group whose gains were not low in the first trimester. The results suggest that specific patterns of maternal weight gain, particularly weight gain during the first trimester, are related to fetal birth weight.

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Effects of Yoga during Pregnancy on Weight Gain, Delivery Experience and Infant's Birth Weight
Eun Sun Ji, Kyoul Ja Cho, Hyun Jeong Kwon
Korean Journal of Women Health Nursing.2009; 15(2): 121. CrossRef

A Case of Cystic Degeneration of Uterine Adenomyosis.: Yang Soo Kwak, Sang Won Lee, Ho Joon WhangBo, Doo Jin Lee, Sung Ho Lee; Yeungnam Univ J Med. 1994;11(2):405-410. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.405

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Abstract PDF: Adenomyosis is a common disease of middle-aged women and adenomyoma is a variety of adenomyosis that formed localized tumor. Cystic degeneration of an adenomyoma is a rare clinical manifestation. A 30-year-old parous woman suffered from severe dysmenorrhea and menorrhagia for about 5 months, was operated under the impression of endometriosis of the pelvis. Following the operation, cystic degeneration of an adenomyoma was found incidentally. The authors experienced a case of adenomyosis that formed cystic tumor of uterus and presented with a pertinent literatures.

Hematologic Status of Newborn Infants of Mother with Pregnancy-induced Hypertension: Doo Jin Lee, Min Whan Koh, Sung Ho Lee; Yeungnam Univ J Med. 1994;11(2):352-362. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.352

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Abstract PDF: To evaluate the effects of pregnancy-induced hypertension (PIH) to the iron status of fetuses, umbilical cord blood of 35 newborn borne by PIH mothers and of 37 normal term infants delivered at Yeungnam University Hospital from September 1, 1993 to September 30, 1994, were studied. The serum hemoglobin concentration of women with PIH was significantly higher than normal full-term pregnant women. There was no significant difference in serum hemoglobin concetration between women with PIH and normal full-term pregnant women and their newborn infants. There was no significant difference in serum hemoglobin concentration between infants iof women with PIH and normal full-term infants. The serum iron concentration of newborn infants of women with PIH was higher and the serum ferritin concentration of newborn infants of women with PIH was lower than normal full-term infants, but there were no significant difference between the two groups. The serum total iron-binding capactity and unsaturated iron-binding capacity of infants of women with PIH were significantly higher than normal full-term infants. The newborn infants of PIH women seemed that they might have occult depletion of iron store and need meticulous follow up during early neonatal period.

Gynecologic Application of the Pelviscopic Surgery.: Seok Bong Koh, Jae Yeoul Lee, Young Gi Lee, Yoon Kee Park, Doo Jin Lee, Tae Hyung Lee, Sung Ho Lee; Yeungnam Univ J Med. 1994;11(1):127-134. Published online June 30, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.1.127

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Abstract PDF: The aim of this study was to identify the usefulness of pelviscopy in treatment besides its diagnostic value. The advantages of pelviscopic surgery are low cost, rapid recovery, good cosmetic effect, low incidence of complication and postoperative adhesion. So most of the pelvic exploration in gynecologic patients are replaced by the pelviscopic surgery these days. Pelviscopic surgery was performed on 136 patients at the Department of Obstetrics and Gynecology, College of Medicine, Yenungnam University from May 1991 to July 1993. The results obtained were as follows : The age distribution of the patients was from 19 to 55 with age of 31.2 years, and the mean parity was 0.96, the most common indication of pelviscopic surgery was tubal pregnancy(66.9%), the second most common indications was ovarian cyst(10.3%) and the other indications were endometriosis, corpus iuteum cyst rupture, parovarian cyst, foreign body, tubal ligation, hydrosalpinx, uterine myoma and in 16.3%. The mean duration of hospitalization was 2.1 days without specific complications. According to these results, it was postulated that the pelviscopic surgery was a useful operative tool in gynecologic treatment and its application could be extended to many other areas of gynecology with safety by the development of surgical techniques and instruments.

A case of Arnold-Chiari malformation.: Jong Ho Kim, Byeong Seog Kim, Mi Na Lee, Doo Jin Lee, Sung Ho Lee; Yeungnam Univ J Med. 1992;9(1):203-209. Published online June 30, 1992; DOI: https://doi.org/10.12701/yujm.1992.9.1.203

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Abstract PDF: The Arnold-Chiari malformation (ACM) is an anomaly of the hindbrain consisting of two components: a variable displacement of a tongue of tissue derived from the inferior cerebellar vermis in the upper cervical canal and a similar caudal dislocation of the medulla and fourth ventricle. Hydrocephalus and meningomyelocele are another abnormalities that associated frequently. We present a case of Arnold-Chiari malformation with hydrocephalus and meningomyeolcele and a brief review of the literatures was added.

A study on the fetal umbilical artery doppler blood flow velocity waveforms in normal pregnancy.: Cheol Seong Bae, Gee Jin Kwun, Doo Jin Lee, Yoon Kee Park, Sung Ho Lee, Kil Ho Cho; Yeungnam Univ J Med. 1991;8(1):63-71. Published online June 30, 1991; DOI: https://doi.org/10.12701/yujm.1991.8.1.63

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Abstract PDF: Noninvasive techniques of antenatal detection of the fetal development and well-being such as biophysical profile, non-stress and stress remain major challenges in modern obstetric practice. To obtain and analyze umbilical artery velocity waveform by pulsed-wave doppler ultrasound, a total of 160 determinations were carried out on 157 normal pregnant women between 16th to 41st week gestation. The ratio of peak systolic to end-diastolic flow velocity (S/D ratio), pulsatility index and resistance index were measured as indices of the resistance in feto-placental circulation. The results were as follows: As gestation advances, the mean values for peak systolic and end-diastolic velocities raised progressively. As gestation advances, the mean values for the S/D ratio declined progressively, exhibiting high diastolic flow velocity caused by low resistance. Pulsatility index, and resistance index were also declined progressively, as gestation advances. The analysis of umbilical artery blood flow velocity waveforms provides a new noninvasive technique to evaluate fetal development and well-being, and may be expected a reliable method for assessment of fetal life.

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